The Advanced Diagnostics and Therapeutics (AD&T) research center announced new awards that will enable faculty researchers to pivot or expand their existing research to address the detection, diagnosis, treatment, or prognosis of COVID-19 viral infections and related serious medical conditions.
T-cells, which hunt for traces of disease within other cells, work by identifying fragments of outsider proteins on a diseased cell’s surface and then go in for the literal kill.
With cancer, some of the mutated fragments of outsider proteins, called neoepitopes, can be recognized by T-cells and are ideal candidates for cancer vaccines. Unfortunately, those candidates are difficult to predict from genetic data alone.
A study published this month in Nature Chemical Biology by Brian Baker, the Rev. John A. Zahm Professor of Structural Biology and chair of the Department of Chemistry and Biochemistry at the University of Notre Dame, and collaborator Alexandre Harari at the Ludwig Institute for Cancer Research at the University of Lausanne (UNIL) in Lausanne, Switzerland shows that to improve those predictions and develop cancer vaccines, researchers need to think more about what neoepitopes look like in three dimensions.
Editor’s note: As classes resume on campus during this unprecedented time, faculty and staff members are, as always, HERE for Notre Dame students. Whether work is done physically on campus or remotely, the collective purpose remains to offer an unsurpassed undergraduate education that nurtures the mind, body and spirit; and to advance human understanding through scholarship, research and post-baccalaureate programs that heal, unify and enlighten. …
Christian Melander, George & Winifred Clark Professor of Chemistry & Biochemistry, and Roberta Melander, Research Associate Professor, with Professor Cassandra Quave and colleagues from Emory University, have reported new research showing that an extract from the American beautyberry plant increases the efficacy of certain antibiotics in the treatment of methicillin-resistant Staphylococcus aureus (MRSA).
Francis J. Castellino, Kleiderer-Pezold Professor of Biochemistry and Director of the W.M. Keck Center for Transgene Research, has been selected as a recipient of the 2020 International Society on Thrombosis and Haemostasis (ISTH) Esteemed Career Award. This prestigious award is given to those who “have made significant contributions to the understanding, treatment and diagnosis, research and education in the thrombosis and hemostasis field.” Five recipients are selected annually.
Students can now earn a distinctive, interdisciplinary doctoral degree in materials science and engineering through the College of Engineering and the College of Science.
Twenty-three students and faculty have been announced as awardees of the Naughton Fellowships for 2020.
Two students from the University of Notre Dame have received fellowships through the Advanced Diagnostics and Therapeutics' Berry Family Foundation Graduate Fellowship Program.
Dan Gezelter, professor in the Department of Chemistry and Biochemistry, has been named associate dean for undergraduate studies for the University of Notre Dame College of Science, effective July 1, 2020.
Fluorescence imaging has been a boon to research and medicine because of its ability to examine affected areas noninvasively. But the dyes used for these purposes have their disadvantages, and as resolution needs have grown stronger, the stakes for accuracy have increased exponentially.
As Notre Dame’s laboratories went into hibernation in March, many researchers from various fields — chemistry, engineering, political science, psychology, education — looked for ways to pivot their own work toward furthering knowledge into how COVID-19, the disease caused by the SARS-CoV-2 virus, works, how it’s transmitted, and how our country and world can cope with the unexpected pandemic crisis. They decided to jump into the research at different times, but for the same reason: They knew they could help.
Gregory Hartland, Professor of Chemistry & Biochemistry, has been named Deputy Editor for the Journal of Physical Chemistry C of the American Chemical Society. The journal focuses on experimental and computational physical chemistry research in energy conversion and storage, heterogeneous catalysis, and the spectroscopy and physical properties of solid-state and nanomaterials.
Six faculty from the University of Notre Dame’s College of Arts and Letters, College of Engineering, and College of Science have been awarded two grants through the NDnano Seed Grant Program.
Steven Corcelli, Professor in the Department of Chemistry & Biochemistry and Associate Dean for Interdisciplinary Studies and Faculty Development, has been selected as the 2020 recipient of the Thomas P. Madden Award. This award honors the faculty member who contributed the most to the teaching of first-year students.
J. Daniel Gezelter, professor in the Department of Chemistry & Biochemistry, is the 2020 recipient of the Father James L. Shilts, C.S.C./Doris and Gene Leonard Teaching Award. This award, given by the Notre Dame College of Science, recognizes excellence in teaching at both the undergraduate and graduate levels.
Marya Lieberman, professor of chemistry and biochemistry, is the 2020 winner of the Reinhold Niebuhr Award in acknowledgement of her work on Paper Analytical Devices (PADs). This award recognizes a faculty member or administrator whose life and body of academic work promotes or exemplifies the pursuit of social justice in modern life.
Professors Jon Camden, Daniel Gezelter, and Paul Helquist have been selected as recipients of the 2020 Rev. Edmund P. Joyce C.S.C. Award for Excellence in Undergraduate Teaching.