Associate Professional Specialist, University of Notre Dame
2008-2017
Assistant Professional Specialist, University of Notre Dame
2003-2007
Postdoctoral Research Associate, University of Notre Dame
2001-2003
Postdoctoral Research Associate, Wayne State University
2002
Ph.D. in Chemistry, Pohang University of Science and Technology, Pohang, South Korea
1995
B.S. in Chemistry, Pohang University of Science and Technology, Pohang, South Korea
Selected Awards
2010
Innovation Fellow, Edison Foundation
2006
Dr. Karl R. Ruddell Scholarship, Walther Cancer Institute
1995
Award of Excellence, Pohang University of Science and Technology
Recent Papers
Dik, D.A., Batuecas, M.T., Lee, M., Mahasenan, K.V., Marous, D.R., Lastochkin, E., Fisher, J.F., Hermoso, J.A., Mobashery, S. "A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli" 2018 Biochemistry, 57 (42), pp. 6090-6098. DOI: 10.1021/acs.biochem.8b00800
Nguyen, T.T., Ding, D., Wolter, W.R., Pérez, R.L., Champion, M.M., Mahasenan, K.V., Hesek, D., Lee, M., Schroeder, V.A., Jones, J.I., Lastochkin, E., Rose, M.K., Peterson, C.E., Suckow, M.A., Mobashery, S., Chang, M. "Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 Inhibitor That Accelerates Healing" 2018 Journal of Medicinal Chemistry, 61 (19), pp. 8825-8837. DOI: 10.1021/acs.jmedchem.8b01005
Nguyen, T.T., Ding, D., Wolter, W.R., Champion, M.M., Hesek, D., Lee, M., Pérez, R.L., Schroeder, V.A., Suckow, M.A., Mobashery, S., Chang, M. "Expression of active matrix metalloproteinase-9 as a likely contributor to the clinical failure of aclerastide in treatment of diabetic foot ulcers" 2018 European Journal of Pharmacology, 834, pp. 77-83. DOI: 10.1016/j.ejphar.2018.07.014
Lee, M., Batuecas, M.T., Tomoshige, S., Domínguez-Gil, T., Mahasenan, K.V., Dik, D.A., Hesek, D., Millán, C., Usón, I., Lastochkin, E., Hermoso, J.A., Mobashery, S. "Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa" 2018 Proceedings of the National Academy of Sciences of the United States of America, 115 (17), pp. 4393-4398. DOI: 10.1073/pnas.1801298115
Bernardo-García, N., Mahasenan, K.V., Batuecas, M.T., Lee, M., Hesek, D., Petráčková, D., Doubravová, L., Branny, P., Mobashery, S., Hermoso, J.A. "Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae" 2018 ACS Chemical Biology, 13 (3), pp. 694-702. DOI: 10.1021/acschembio.7b00817
Kim, C., Hesek, D., Lee, M., Mobashery, S. "Potentiation of the activity of β-lactam antibiotics by farnesol and its derivatives" 2018 Bioorganic and Medicinal Chemistry Letters, 28 (4), pp. 642-645. DOI: 10.1016/j.bmcl.2018.01.028
