Department of Chemistry & Biochemistry

Biography

2016-present

Concurrent Professor, Department of Chemistry & Biochemistry, University of Notre Dame

2016-present

Professor, Department of Chemical & Biomolecular Engineering, University of Notre Dame

2007-2016

Professor, Michigan State University

2002-2007

Associate Professor, Michigan State University

1997-2002

Assistant Professor, Michigan State University

1995-1997

NIH Postdoctoral Fellow, Texas A&M University

1995

Ph.D. in Chemistry, The Weizmann Institute of Science

1990

M.S. in Chemistry, Brigham Young University

1989

B.S. in Chemical Engineering, Brigham Young University

Selected Awards

2016

Benedetti-Pichler Award of the American Microchemical Society

2015

MSU Innovation of the Year

2014

MSU College of Natural Science Distinguished Faculty Award

2000

Society for Electroanalytical Chemistry Young Investigator Award

Research Interests

The Bruening Group develops new thin films for specific protein capture in porous membranes, ion separations in electrodialysis, and controlled protein digestion prior to analysis with mass spectrometry. Potential applications include protein purification, antibody characterization and sequencing, and salt purification or recycling.

Recent Papers

• Liu, W., Pang, Y., Tan, H.-Y., Patel, N., Jokhadze, G., Guthals, A., Bruening, M.L. "Enzyme-containing spin membranes for rapid digestion and characterization of single proteins" 2018 Analyst, 143 (16), pp. 3907-3917. DOI: 10.1039/c8an00969d
• Liu, W., Wijeratne, S., Yang, L., Bruening, M. "Porous star-star polyelectrolyte multilayers for protein binding" 2018 Polymer (United Kingdom), 138, pp. 267-274. DOI: 10.1016/j.polymer.2018.01.055
• Yang, Z., Zhang, S., Tarabara, V.V., Bruening, M.L. "Aqueous Swelling of Zwitterionic Poly(sulfobetaine methacrylate) Brushes in the Presence of Ionic Surfactants" 2018 Macromolecules, 51 (3), pp. 1161-1171. DOI: 10.1021/acs.macromol.7b01830
• Dong, J., Ning, W., Liu, W., Bruening, M.L. "Limited proteolysis in porous membrane reactors containing immobilized trypsin" 2017 Analyst, 142 (14), pp. 2578-2586. DOI: 10.1039/c7an00778g
• Yaroshchuk, A., Bruening, M.L. "An analytical solution of the solution-diffusion-electromigration equations reproduces trends in ion rejections during nanofiltration of mixed electrolytes" 2017 Journal of Membrane Science, 523, pp. 361-372. DOI: 10.1016/j.memsci.2016.09.046
• Zhu, Y., Ahmad, M., Yang, L., Misovich, M., Yaroshchuk, A., Bruening, M.L. "Adsorption of polyelectrolyte multilayers imparts high monovalent/divalent cation selectivity to aliphatic polyamide cation-exchange membranes" 2017 Journal of Membrane Science, 537, pp. 177-185. DOI: 10.1016/j.memsci.2017.05.043