Merlin Bruening

Merlin Bruening

Thin Films for Selective Protein Separations


Concurrent Professor, Department of Chemistry & Biochemistry, University of Notre Dame
Professor, Department of Chemical & Biomolecular Engineering, University of Notre Dame
Professor, Michigan State University
Associate Professor, Michigan State University
Assistant Professor, Michigan State University
NIH Postdoctoral Fellow, Texas A&M University
Ph.D. in Chemistry, The Weizmann Institute of Science
M.S. in Chemistry, Brigham Young University
B.S. in Chemical Engineering, Brigham Young University

Selected Awards

Benedetti-Pichler Award of the American Microchemical Society
MSU Innovation of the Year
MSU College of Natural Science Distinguished Faculty Award
Society for Electroanalytical Chemistry Young Investigator Award

Research Interests

The Bruening Group develops new thin films for specific protein capture in porous membranes, ion separations in electrodialysis, and controlled protein digestion prior to analysis with mass spectrometry. Potential applications include protein purification, antibody characterization and sequencing, and salt purification or recycling.

Recent Publications

  • Bondarenko, M. P., Bruening, M. L., Yaroshchuk, A. "Electro-osmo-dialysis through nanoporous layers physically conjugated to micro-perforated ion-exchange membranes: Highly selective accumulation of trace coions" 2021 Journal of Membrane Science, 622, 119022.  DOI:10.1016/j.memsci.2020.119022.
  • Zhang, S., Yang, L., Ding, D., Gao, P., Xia, F., Bruening, M. L. "Highly Rectifying Fluidic Diodes Based on Asymmetric Layer-by-Layer Nanofilms on Nanochannel Membranes" 2021 Analytical Chemistry, 93 (9), pp. 4291-4298. DOI:10.1021/acs.analchem.0c05303.
  • Ahmad, M., Yaroshchuk, A., Bruening, M. L. "Moderate pH changes alter the fluxes, selectivities and limiting currents in ion transport through polyelectrolyte multilayers deposited on membranes" 2020 Journal of Membrane Science, 616, 118570.  DOI:10.1016/j.memsci.2020.118570.
  • Bondarenko, M. P., Bruening, M. L., Yaroshchuk, A. E. "Current-Induced Ion Concentration Polarization at a Perfect Ion-Exchange Patch in an Infinite Insulating Wall" 2020 ChemElectroChem, 7 (6), pp. 1480-1498. DOI:10.1002/celc.201902068.
  • Tummons, E. N., Hejase, C. A., Yang, Z., Chew, J. W., Bruening, M. L., Tarabara, V. V. "Oil droplet behavior on model nanofiltration membrane surfaces under conditions of hydrodynamic shear and salinity" 2020 Journal of Colloid and Interface Science, 560 pp. 247-259. DOI:10.1016/j.jcis.2019.10.012.
  • Ahmad, M., Tang, C., Yang, L., Yaroshchuk, A., Bruening, M. L. "Layer-by-layer modification of aliphatic polyamide anion-exchange membranes to increase Cl−/SO42− selectivity" 2019 Journal of Membrane Science, 578 pp. 209-219. DOI:10.1016/j.memsci.2019.02.018.

Contact Information

Primary Research Areas

Research Specialties