Marya Lieberman

Marya Lieberman

Surface Chemistry

Biography

2016-present
Professor, University of Notre Dame
2002-2016
Associate Professor, University of Notre Dame
1996-2002
Assistant Professor, University of Notre Dame
1994-1996
Postdoctoral Fellow, California Institute of Technology
1994
Ph.D. in Chemistry, University of Washington
1989
B.S. in Chemistry, Massachusetts Institute of Technology

Selected Awards

2015
Partners for Progress Prosperity (P3) Award, ACS Joint Great Lakes/Central Region
2010
Joyce Award for Excellence in Undergraduate Teaching
2010-2011
Kaneb Faculty Fellow
2001-present
Reilly Fellow
1998
NSF Career Award
1994-1996
NSF Postdoctoral Fellowship

Research Interests

Paper Analytical Devices

In the early 2000's, researchers discovered that nearly half of the antimalarial medications in some developing countries were fake. These products caused over 120,000 deaths per year. IR, NMR, and HPLC can easily measure the quality of essential medicines, so why are bad quality products killing people in the developing world? The problem is that these technologies are designed for countries with abundant resources. But expensive instruments, trained operators, and high purity supplies are just unavailable in many places in the world. The development of new technologies that are scalable and implementable in low resource settings is a compelling research problem that can impact people's lives all over the world. 

My lab is designing paper analytical devices (PADs) to solve a host of analytical problems in low resource settings. Paper is printed with hydrophobic ink to create millifluidic structures such as solution channels, reagent storage areas, and mixing zones. This enables us to automate operations that would normally be carried out with glassware in a lab setting. Many reactions and assay methods used before the age of spectroscopy can be adapted to the paper platform and done in a field setting rather than a laboratory. Current work focuses on synthetic biology for creating biosensors to embed in the paper and on techniques for trace (ppm, ppb) analysis in paper-based systems. 

Paper test cards made in our group have been trialed in Britain, the US, Israel, Tanzania, the Philippines, India, South Africa, Burkina Faso, Kenya, Uganda, Sudan, Ethiopia, Malawi, Liberia, and Ghana, and by non-governmental organizations such as Médecins Sans Frontières, SIDAI, and MITI Health. Design and prototyping is an integral part of the projects, and researchers in my group travel for field tests in Kenya, Malawi, Uganda, or Nepal.

Recent Papers

  • Chikowe, I., Bliese, S.L., Lucas, S., Lieberman, M. "Amoxicillin quality and selling practices in urban pharmacies and drug stores of Blantyre, Malawi" 2018 American Journal of Tropical Medicine and Hygiene, 99 (1), pp. 233-238. DOI: 10.4269/ajtmh.18-0003
  • Luther, J.L., Henry De Frahan, V., Lieberman, M. "Paper test card for detection of adulterated milk" 2017 Analytical Methods, 9 (38), pp. 5674-5683. DOI: 10.1039/c7ay01321c
  • Myers, N.M., Leung, I.C., McGee, S.W., Eggleson, K., Lieberman, M. "Green design of a paper test card for urinary iodine analysis" 2017 PLoS ONE, 12 (6), e0179716. DOI: 10.1371/journal.pone.0179716
  • Tran, D.N., Njuguna, B., Mercer, T., Manji, I., Fischer, L., Lieberman, M., Pastakia, S.D. "Ensuring Patient-Centered Access to Cardiovascular Disease Medicines in Low-Income and Middle-Income Countries Through Health-System Strengthening" 2017 Cardiology Clinics, 35 (1), pp. 125-134. DOI: 10.1016/j.ccl.2016.08.008​​​​​​​
  • Banerjee, S., Sweet, J., Sweet, C., Lieberman, M. "Visual recognition of paper analytical device images for detection of falsified pharmaceuticals" 2016 2016 IEEE Winter Conference on Applications of Computer Vision, 7477598. DOI: 10.1109/WACV.2016.7477598
  • Myers, N.M., Strydom, E.E., Sweet, J., Sweet, C., Spohrer, R., Dhansay, M.A., Lieberman, M. "saltPAD: A New Analytical Tool for Monitoring Salt Iodization in Low Resource Settings" 2016 Nanobiomedicine, 3. DOI: 10.5772/62919

Contact Information

Primary Research Areas

Research Specialties