Aktar Ali

Aktar Ali

Associate Research Professor


Associate Research Professor & Director, Biological Screening Core, Warren Family Center for Drug Discovery, University of Notre Dame
Adjunct Teaching Faculty, Richland College
Co-Director, Mineral Metabolism Laboratory, University of Texas Southwestern Medical Center
Assistant Professor & Core Director, Biomedical & Obesity Research Core, University of Nebraska
Assistant Professor & Core Director, Metabolic Phenotyping Core, University of Texas Southwestern Medical Center
Instructor, University of Texas Southwestern Medical Center
Associate Research Scientist, Department of Pathology, NYU School of Medicine
Assistant Research Scientist, Nelson Institute of Environmental Medicine, NYU School of Medicine
Postdoctoral Fellow, Niigata University of Pharmacy and Applied Life Science, Japan
Ph.D. in Pharmaceutical Science, Niigata University of Pharmacy and Applied Life Science, Japan
M.Sc. in Inorganic Chemistry, University of Chittagong, Bangladesh
B.Sc. in Chemistry, University of Chittagong, Bangladesh

Recent Publications

  • Tsunezumi, J.; Sugiura, H.; Oinam, L.; Ali, A.; Thang, B. Q.; Sada, A.; Yamashiro, Y.; Kuro-O, M. and Yanagisawa, H. "Fibulin-7, a Heparin Binding Matricellular Protein, Promotes Renal Tubular Calcification in Mice" 2018 Matrix Biology, 74, pp.5-20. DOI: 10.1016/j.matbio.2018.04.014.
  • Deng, Y. F.; Wang, Z. V.; Gordillo, R.; Zhu, Y.; Ali, A.; Zhang, C.; Wang, X. D.; Shao, M. L.; Zhang, Z. Z.; Iyengar, P.; Gupta, R. K.; Horton, J. D.; Hill, J. A. and Scherer, P. E. "Adipocyte Xbp1s Overexpression Drives Uridine Production and Reduces Obesity" 2018 Molecular Metabolism, 11, pp.1-17. DOI: 10.1016/j.molmet.2018.02.013.
  • Hasan, M.; Gonugunta, V. K.; Dobbs, N.; Ali, A.; Palchik, G.; Calvaruso, M. A.; DeBerardinis, R. J. and Yan, N. "Chronic Innate Immune Activation of TBK1 Suppresses mTORC1 Activity and Dysregulates Cellular Metabolism" 2017 Proceedings of the National Academy of Sciences of the United States of America, 114 (4), pp.746-751. DOI: 10.1073/pnas.1611113114.
  • Wang, Q. A.; Tao, C.; Jiang, L.; Shao, M. L.; Ye, R. S.; Zhu, Y.; Gordillo, R.; Ali, A.; Lian, Y.; Holland, W. L.; Gupta, R. K. and Scherer, P. E. "Distinct Regulatory Mechanisms Governing Embryonic Versus Adult Adipocyte Maturation" 2015 Nature Cell Biology, 17 (9), pp.1099. DOI: 10.1038/ncb3217.
  • Moore, Z.; Chakrabarti, G.; Luo, X.; Ali, A.; Hu, Z.; Fattah, F. J.; Vemireddy, R.; DeBerardinis, R. J.; Brekken, R. A. and Boothman, D. A. "NAMPT Inhibition Sensitizes Pancreatic Adenocarcinoma Cells to Tumor-Selective, PAR-Independent Metabolic Catastrophe and Cell Death Induced by Beta-Lapachone" 2015 Cell Death & Disease, 6, e1599. DOI: 10.1038/cddis.2014.564.
  • Chakrabarti, G.; Moore, Z. R.; Luo, X.; Ilcheva, M.; Ali, A.; Padanad, M.; Zhou, Y.; Xie, Y.; Burma, S.; Scaglioni, P. P.; Cantley, L. C.; DeBerardinis, R. J.; Kimmelman, A. C.; Lyssiotis, C. A. and Boothman, D. A. "Targeting Glutamine Metabolism Sensitizes Pancreatic Cancer to PARP-Driven Metabolic Catastrophe Induced by SS-Lapachone" 2015 Cancer & Metabolism, 3, pp.12. DOI: 10.1186/s40170-015-0137-1.

Contact Information

  • Associate Research Professor
  • Office: 305B McCourtney Hall
  • Phone: 574-631-2363
  • Send an email

Primary Research Areas

Research Specialties