Başar Bilgiçer
Concurrent Professor
- Office
- 205C McCourtney Hall - West
- bbilgicer@nd.edu
Research Areas
- Biochemistry
Research Specialties
- Medicine
- Synthesis
Prospective Graduate Students
Biography
| Year | Title |
|---|---|
| 2021-present | Professor, Dept. of Chemical & Biomolecular Engineering, University of Notre Dame |
| 2021-present | Concurrent Professor, Dept. of Chemistry & Biochemistry, University of Notre Dame |
| 2015-2021 | Associate Professor, Dept. of Chemical & Biomolecular Engineering, University of Notre Dame |
| 2015-2021 | Concurrent Associate Professor, Dept. of Chemistry & Biochemistry, University of Notre Dame |
| 2008-2015 | Assistant Professor, Dept. of Chemical & Biomolecular Engineering, University of Notre Dame |
| 2008-2015 | Concurrent Assistant Professor, Dept. of Chemistry & Biochemistry, University of Notre Dame |
| 2005-2008 | Postdoctoral Fellow, Harvard University |
| 2005 | Ph.D. in Chemistry, Tufts University |
| 1998 | B.S. in Chemistry, Bogazici University, Turkey |
Research Interests
Multivalent biomolecular interactions are very important in biological systems. A deeper understanding of the thermodynamics and kinetics of multivalent interactions in biological systems is imperative in the development of new diagnostic and therapeutic agents. My lab focuses on both understanding the basic dynamic principles of multivalent biomolecular interactions, as well as design of multivalent therapeutic and diagnostic molecules which will deliver novel solutions to complex diseases (e.g. cancer, autoimmune diseases, and allergies).
Selected Publications
- Cannon, A.; Zhang, J. L.; Ropa, J.; Pajulas, A.; Cheung, C.; Niese, M. L.; Abdelaal, A. M.; Khan, S.; Bromley, E.; Hwang, G.; Krishnan, M.; Bilgicer, B.; Mastracci, T. L.; Schwartz, D. M. and Kaplan, M. H. "Macrophage-Intrinsic and IL-9-Dependent Arginine Metabolism Promotes Lung Tumor Growth" 2026 Journal of Immunology, 215 (3), vkag026. DOI: 10.1093/jimmun/vkag026.
- Bromley, E. K.; Sjoerdsma, J. N.; Horgan, C. L.; Smith, S. A.; Khan, D. A.; Phillips, E. J.; Blumenthal, K. G.; Stone, C. A. and Bilgicer, B. "Engineering Nanoallergens to Investigate Origins of Immunogenicity and Cross-Reactivity in Cephalosporin Allergy" 2025 Journal of Allergy and Clinical Immunology, 155 (6), pp.1957-1967. DOI: 10.1016/j.jaci.2025.02.022.
- Sjoerdsma, J. N.; Bromley, E. K.; Shin, J.; Hilliard, T.; Liu, Y. Y.; Horgan, C.; Hwang, G.; Bektas, M.; Omstead, D.; Kiziltepe, T.; Stack, M. S. and Bilgicer, B. "Combination Non-Targeted and sGRP78-Targeted Nanoparticle Drug Delivery Outperforms either Component to Treat Metastatic Ovarian Cancer" 2024 Journal of Controlled Release, 375 pp.438–453. DOI: 10.1016/j.jconrel.2024.09.014.
- Bilgicer, B. and Kaplan, M. H. "Allergen-Specific IgE Inhibitors Block Anaphylactic Responses by Targeting Allergen Recognition" 2024 Journal of Allergy and Clinical Immunology, 153 (3), pp.663-665. DOI: 10.1016/j.jaci.2024.01.009.
- Shin, J.; Kim, B.; Lager, T. W.; Mejia, F.; Guldner, I.; Conner, C.; Zhang, S. Y.; Panopoulos, A. D. and Bilgicer, B. "A Nanotherapeutic Approach to Selectively Eliminate Metastatic Breast Cancer Cells by Targeting Cell Surface GRP78" 2023 Nanoscale, 15 (32), pp.13322-13334. DOI: 10.1039/d3nr00800b.
- Alakhras, N. S.; Shin, J.; Smith, S. A.; Sinn, A. L.; Zhang, W. W.; Hwang, G.; Sjoerdsma, J.; Bromley, E. K.; Pollok, K. E.; Bilgicer, B. and Kaplan, M. H. "Peanut Allergen Inhibition Prevents Anaphylaxis in a Humanized Mouse Model" 2023 Science Translational Medicine, 15 (682), eadd6373. DOI: 10.1126/scitranslmed.add6373.