Notre Dame researchers, along with their collaborators, have identified a novel target of artemisinin that is crucial in understanding the mechanism of resistance in malarial parasites. These findings are reported in the April 30, 2015 issue of Nature. The team's results show that targeting PfPl3K will be vital to developing new therapies to combat artemisinin resistance.
Researchers in the Hartland group, along with their collaborators at the University of Melbourne, have published new research in Nano Letters showing that at the nanoscale, even simple liquids can act like viscoelastic liquids. This is the first time that compressional viscoelastic effects have been seen in simple liquids.
An accomplished scientist with extensive experience in the academic, government and private sectors, Mary E. Galvin has been appointed the William K. Warren Foundation Dean of the College of Science at the University of Notre Dame by Rev. John I. Jenkins, C.S.C., the University’s president.
Marya Lieberman, associate professor of chemistry and biochemistry and member of the Eck Institute for Global Health, was awarded the inaugural Partners for Progress Prosperity (P3) Award at the American Chemical Society (ACS) 2015 Joint Great Lakes/Central Regional Meeting on Friday (May 29). She was recognized for her partnerships with Moi Teaching and Referral Hospital in Kenya and Chemists Without Borders.
Robert V. Stahelin, adjunct associate professor of chemistry and biochemistry at the University of Notre Dame and associate professor of biochemistry and molecular biology at Indiana University School of Medicine-South Bend (IUSM-SB), has been awarded IUSM-SB's Navari Family Endowed Chair.
During Commencement season 2015, the Graduate School bestowed four prestigious awards: the Distinguished Alumnus Award; the James A. Burns, CSC Award; the Director of Graduate Studies Award; and the Graduate Administrative Staff Member Award.
First-year graduate student Elizabeth Peuchen is an awardee in the 2015 Graduate Research Fellowships Program (GRFP) from the National Science Foundation (NSF). Eight College of Science students and two alumni received awards. In addition, several students and alumni received honorable mentions. There were over 16,000 applications for this year's GRFP with 2,000 awardees nationwide.
A group of researchers, led by Prof. Jon Camden, has reported the first nanoscale mapping of the flow of energy between light-harvesting plasmonic nanoparticles and semiconductor substrates. This work demonstrates an exciting new method for researchers to use in probing competing energy transfer mechanisms in nanoparticle on semiconductor systems.
To say that Dr. Amanda Hummon is busy these days—even by Notre Dame standards of busy—would be an understatement. She insists otherwise, of course. But consider this: In addition to teaching classes to Notre Dame undergraduates, Hummon is guiding no less than four major research projects this academic year on varying aspects of cancer research. Read more...
Maggie Kerper came to college interested in science, but really developed a passion for the field after taking her first college-level science classes. After transferring to Notre Dame as a sophomore, she decided to find ways to explore science outside of the classroom.
Kerper began working with Laurie Littlepage, Campbell Assistant Professor of Cancer Research in the Department of Chemistry and Biochemistry, during the spring of her sophomore year. “I went to an extra credit talk given by Prof. Littlepage and was so impressed and interested in her work. I had no idea cancer research opportunities like this existed on campus,” she explains. “I immediately felt drawn to get involved. I can’t think of any other field that I would feel the sort of gratification and drive to work harder than the cancer field.”
Estimates of deaths from methicillin-resistant Staphylococcus aureus (MRSA) in the United States range upwards of 19,000 annually. Around 1960, when Staphylococcus aureus developed resistance to first-generation penicillin, methicillin and other second-generation beta-lactam antibiotics were adopted to fight the illness. The modern variants of the bacterium have developed resistance to the four drugs now used to treat it.
A team of researchers led by Shahriar Mobashery and Mayland Chang at the University of Notre Dame has discovered a promising new antibiotic, a vital weapon against disease as pathogens evolve to develop resistance to long-used drugs.
Steven Corcelli, professor of chemistry and biochemistry and director of graduate studies, has been appointed as chair of the Graduate Education Advisory Board (GEAB) in 2015.
Diabetes affects more than 29 million Americans, or 9.3 percent of the population. One of the many complications of the disease is the inability of wounds to heal properly because diabetic patients often have nerve damage, weakened immune systems or narrow arteries. In 2010, 73,000 non-traumatic lower-limb amputations were performed in the United States due to diabetes.
The American Diabetes Association (ADA) announced Tuesday that it is funding a $1.6 million Accelerator Award to Mayland Chang, research professor of chemistry and biochemistry at the University of Notre Dame, to help lower that number. The research award, part of the association’s Pathway Awards program, will provide funding for Chang’s project, “A Strategy to Accelerate Diabetic Wound Repair,” over five years.
Notre Dame and Saint Joseph Regional Medical Center, a member of the Trinity Health system, have announced that they are collaborating on research aimed at earlier detection of sepsis in patients. Sepsis, a potentially fatal illness in which the body has a severe inflammatory response to bacteria or other microorganisms, is the leading cause of death from infection in the world and is the costliest condition to U.S. hospitals.
Renee Bouley, a fourth-year graduate student in the Department of Chemistry and Biochemistry, has received a Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship from the National Institutes of Health (NIH). The fellowship will provide two years of funding for Bouley’s project, “Discovery of a new class of antibacterials that inhibits penicillin-binding proteins.”
A new study by Robert Stahelin, an adjunct associate professor of chemistry and biochemistry at the University of Notre Dame and an associate professor at the Indiana University School of Medicine-South Bend, as well as a member of Notre Dame’s Eck Institute for Global Health, investigates how the most abundant protein that composes the Ebola virus, VP40, mediates replication of a new viral particle.
Garima Agrahari, graduate student in the laboratory of Francis J. Castelllino, is a recent recipient of a two year predoctoral fellowship from the Midwest Affiliate of the American Heart Association. The title of her study is “Molecular mechanisms of antiphagocytic activity mediated by Plasminogen binding group A streptococcal M-like protein.”