News

New Research Director Joins Notre Dame’s Advanced Diagnostics & Therapeutics

Author: Arnie Phifer

Aaron Timperman, Ph.D., has joined the University of Notre Dame’s Advanced Diagnostics & Therapeutics (AD&T) initiative as its new Associate Director-Research. “Aaron is an analytical scientist and bioengineer with extensive experience in many of the areas at the core of AD&T’s R&D portfolio,” Paul Bohn, Schmitt Professor of Chemical and Biomolecular Engineer and Director of AD&T, said. Timperman will have a concurrent appointment in the Department of Chemistry and Biochemistry.

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Patricia Clark elected to Executive Council of the Protein Society

Author: Stephanie Healey

Patricia Clark

Patricia Clark, the Rev. John Cardinal O'Hara C.S.C Professor of Biochemistry, has been elected to the executive council of the Protein Society. She will serve a three-year term (2015-18), during which she will work with the other councilors to organize and conduct the society’s business and help plan conferences and other activities for the organization’s membership.

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Three universities host an international summer chemistry program in Santiago, Chile

Author: Stephanie Healey

Chemistry lab

Twenty doctoral students from Europe, Latin America, and the United States are participating in the Santander International Summer School on molecular catalysts from July 14-24 at the Heidelberg Center for Latin America in Santiago, Chile. Organized by the University of Notre Dame, University of Heidelberg in Germany, and the Pontifical Catholic University of Chile (PUC) in Santiago, the summer school will highlight the fundamentals and current developments in the field of molecular catalysts, with an emphasis on catalysts as synthetic tools.

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STEM research leaders call for change in undergrad education

Author: William G. Gilroy

Undergraduates in 2012 Dan Philpott course

Immediate change is needed at all levels to improve the quality of science, technology, engineering and mathematics (STEM) education in research universities, according to a paper on undergraduate STEM learning and teaching co-authored by Zachary Schultz, associate professor of chemistry and biochemistry at the University of Notre Dame, that appears in a special July issue of the journal Nature.

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New paper describes novel synthesis of hyperbranched polymers

Author: William G. Gilroy

Haifeng Gao

A new paper by a team of researchers that includes Haifeng Gao, an assistant professor of chemistry and biochemistry at the University of Notre Dame, presents, for the first time, a one-pot, one-batch synthesis of hyperbranched polymers with tunablemolecular weights, uniform size and high degree of branching using an efficient click polymerization technique.

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New research cluster at Notre Dame accelerates cancer research

Author: Kallie O'Connell

Dynamics of a tumor neoepitope presented by Major Histocompatibility Complex

With cancer affecting millions of lives each year, Notre Dame scientists are working to develop personalized cancer vaccine therapies with the help of computational modeling. The recent acquisition of a General Purpose Graphics Processing Unit (GPGPU) computer cluster has significantly accelerated output for Notre Dame researchers. Led by Brian Baker, associate dean for research and graduate studies in the College of Science and professor of chemistry and biochemistry, an interdisciplinary team of biophysicists, biochemists and immunologists are using the GPGPU cluster to develop new immunotherapeutics. The cluster is maintained and housed by the Center for Research Computing at Union Station Technology Center, downtown South Bend.

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Summer program in computational chemistry held in Heidelberg, Germany

Author: Stephanie Healey

Heidelberg, Germany

The first Joint Summer School in Computational Chemistry was held at Heidelberg University in Germany July 6-11. Organized by the Department of Chemistry and Biochemistry at the University of Notre Dame and the Institute of Inorganic Chemistry and Interdisciplinary Center for Scientific Computing at Heidelberg University, the six day program provided the opportunity for students who primarily work on experimental research to combine their studies with theory-based approaches, in particular with electronic-structure-based computational chemistry.

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Notre Dame Researchers Work to Identify Mechanisms of Artemisinin Resistant Malaria

Author: Rebecca Hicks

dhabinding

Notre Dame researchers, along with their collaborators, have identified a novel target of artemisinin that is crucial in understanding the mechanism of resistance in malarial parasites. These findings are reported in the April 30, 2015 issue of Nature. The team's results show that targeting PfPl3K will be vital to developing new therapies to combat artemisinin resistance.

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Marya Lieberman earns Partners for Progress and Prosperity Award

Author: Stephanie Healey

Marya Lieberman

Marya Lieberman, associate professor of chemistry and biochemistry and member of the Eck Institute for Global Health, was awarded the inaugural Partners for Progress Prosperity (P3) Award at the American Chemical Society (ACS) 2015 Joint Great Lakes/Central Regional Meeting on Friday (May 29).  She was recognized for her partnerships with Moi Teaching and Referral Hospital in Kenya and Chemists Without Borders.

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Stahelin named recipient of Navari gift

Author: Gail Hinchion Mancini

Rob Stahelin

Robert V. Stahelin, adjunct associate professor of chemistry and biochemistry at the University of Notre Dame and associate professor of biochemistry and molecular biology at Indiana University School of Medicine-South Bend (IUSM-SB), has been awarded IUSM-SB's Navari Family Endowed Chair.

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Graduate School honors Steven Corcelli

Author: Mary Hendriksen

Steven Corcelli

During Commencement season 2015, the Graduate School bestowed four prestigious awards: the Distinguished Alumnus Award; the James A. Burns, CSC Award; the Director of Graduate Studies Award; and the Graduate Administrative Staff Member Award.

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Elizabeth Peuchen earns an NSF Graduate Research Fellowship

Author: Stephanie Healey

First-year graduate student Elizabeth Peuchen is an awardee in the 2015 Graduate Research Fellowships Program (GRFP) from the National Science Foundation (NSF). Eight College of Science students and two alumni received awards. In addition, several students and alumni received honorable mentions. There were over 16,000 applications for this year's GRFP with 2,000 awardees nationwide.

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Notre Dame researchers report first nanoscopic mapping of energy transfer between single plasmonic particles and semiconductor substrates

Author: Rebecca Hicks

NanoLett paper image

A group of researchers, led by Prof. Jon Camden, has reported the first nanoscale mapping of the flow of energy between light-harvesting plasmonic nanoparticles and semiconductor substrates. This work demonstrates an exciting new method for researchers to use in probing competing energy transfer mechanisms in nanoparticle on semiconductor systems.

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Chemistry In Motion

Author: Michael Rodio

Hummon in lab

To say that Dr. Amanda Hummon is busy these days—even by Notre Dame standards of busy—would be an understatement. She insists otherwise, of course. But consider this: In addition to teaching classes to Notre Dame undergraduates, Hummon is guiding no less than four major research projects this academic year on varying aspects of cancer research. Read more...

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Investigating aggressive, lethal breast tumors of Kenyan cancer patients

Author: Stephanie Healey

Maggie Kerper

Maggie Kerper came to college interested in science, but really developed a passion for the field after taking her first college-level science classes. After transferring to Notre Dame as a sophomore, she decided to find ways to explore science outside of the classroom.   

Kerper began working with Laurie Littlepage, Campbell Assistant Professor of Cancer Research in the Department of Chemistry and Biochemistry, during the spring of her sophomore year. “I went to an extra credit talk given by Prof. Littlepage and was so impressed and interested in her work. I had no idea cancer research opportunities like this existed on campus,” she explains. “I immediately felt drawn to get involved. I can’t think of any other field that I would feel the sort of gratification and drive to work harder than the cancer field.”

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New antibiotic holds promise against antibiotic-resistant infections

Author: Gene Stowe

Mayland Chang and Shahriar Mobashery

Estimates of deaths from methicillin-resistant Staphylococcus aureus (MRSA) in the United States range upwards of 19,000 annually. Around 1960, when Staphylococcus aureus developed resistance to first-generation penicillin, methicillin and other second-generation beta-lactam antibiotics were adopted to fight the illness. The modern variants of the bacterium have developed resistance to the four drugs now used to treat it.

A team of researchers led by Shahriar Mobashery and Mayland Chang at the University of Notre Dame has discovered a promising new antibiotic, a vital weapon against disease as pathogens evolve to develop resistance to long-used drugs.

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