Ian Carmichael
Professor; Director, Notre Dame Radiation Laboratory
- Office
- 323 Radiation Research Building
Notre Dame, IN 46556-5674 - Phone
- +1 574-631-4502
- carmichael.1@nd.edu
Research Areas
- Physical/Analytical Chemistry
Research Specialties
- Energy
- Theory
Prospective Graduate Students
Biography
| Year | Title |
|---|---|
| 2004-present | Director, Notre Dame Radiation Laboratory |
| 2004-present | Professor, University of Notre Dame |
| 2001-2004 | Professional Specialist, Notre Dame Radiation Laboratory |
| 1988-2001 | Associate Professional Specialist, Notre Dame Radiation Laboratory |
| 1980-1988 | Assistant Professional Specialist, Notre Dame Radiation Laboratory |
| 1976-1980 | Research Associate, Notre Dame Radiation Laboratory |
| 1974-1976 | British Royal Society Research Fellow, University of Amsterdam, Netherlands |
| 1974 | Ph.D. in Physical and Theoretical Chemistry, University of Glasgow, Scotland |
| 1971 | B.Sc. in Chemistry, University of Glasgow, Scotland |
Research Interests
Ionizing radiation pervades our environment and affects all life on earth. The absorption of this impinging energy produces profound chemical and biochemical transformations in the materials irradiated. Professor Carmichael's research provides a fundamental molecular-level understanding of these radiation effects in matter.
The work is performed in the Notre Dame Radiation Laboratory, the premier facility for radiation chemical research in the US, supported by the Chemical Sciences Division of Basic Energy Sciences at the US Department of Energy. The NDRL provides not only access to unique experimental tools but also outstanding research opportunities for focused interdisciplinary collaborations. Knowledge gained from this research provides the scientific basis for solving problems ranging from the chemical conversion of solar energy, through nuclear energy production, environmental waste management and remediation, to biomedical radiation therapy.
Specific topics currently under active investigation include:
Radiation damage in protein crystallography
Understanding and mitigating radiation damage during macromolecular crystallography at synchrotrons
Electron-driven processes in condensed phases
Excited species in water radiolysis; radical formation in irradiated organic liquids
Radiation effects in heterogeneous systems and at interfaces
Characterizing radiation chemistry at water - ceramic oxide interfaces
Spin coupling in biomolecular NMR
Probing conformational and chemical changes in carbohydrates
Selected Publications
- Meredith, R. J.; Yoon, M. K.; Carmichael, I. and Serianni, A. S. "MA'AT Analysis: Unbiased Multi-State Conformational Modeling of Exocyclic Hydroxymethyl Group Conformation in Methyl Aldohexopyranosides" 2024 Journal of Physical Chemistry B, 128 (10), pp.2360-2370. DOI: 10.1021/acs.jpcb.3c08136.
- Zhang, W. H.; Meredith, R. J.; Wang, X. C.; Woods, R. J.; Carmichael, I. and Serianni, A. S. "Does Inter-Residue Hydrogen Bonding in Β-(1→4)-Linked Disaccharides Influence Linkage Conformation in Aqueous Solution?" 2024 Journal of Physical Chemistry B, 128 (10), pp.2317-2325. DOI: 10.1021/acs.jpcb.3c07448.
- Meredith, R.; Zhu, Y. P.; Yoon, M. K.; Tetrault, T.; Lin, J. Y.; Zhang, W. H.; McGurn, M.; Cook, E.; Popp, R.; Shit, P.; Carmichael, I. and Serianni, A. S. "Methyl Α-D-Galactopyranosyl-(1→3)-Β-D-Galactopyranoside and Methyl Β-D-Galactopyranosyl-(1→3)-Β-D-Galactopyranoside: Glycosidic Linkage Conformation Determined from MA'AT Analysis" 2024 Magnetic Resonance in Chemistry, pp.1-12. DOI: 10.1002/mrc.5424.
- Chakraborty, D.; Kharchilava, G.; Carmichael, I. and Ptasinska, S. "Dissociative Electron Attachment Studies of Gas-Phase Acetic Acid using a Velocity Map Imaging Technique" 2023 Journal of Physics B-Atomic Molecular and Optical Physics, 56 (24), 245202. DOI: 10.1088/1361-6455/ad1745.
- Meredith, R. J.; Carmichael, I.; Woods, R. J. and Serianni, A. S. "MA'AT Analysis: Probability Distributions of Molecular Torsion Angles in Solution from NMR Spectroscopy" 2023 Accounts of Chemical Research, 56 (17), pp.2313-2328. DOI: 10.1021/acs.accounts.3c00286.
- Lisouskaya, A.; Schiemann, O. and Carmichael, I. "Unveiling the Mechanism of Photodamage to Sphingolipid Molecules Via Laser Flash Photolysis and EPR" 2023 Photochemistry and Photobiology, in press. DOI: 10.1111/php.13804.