Cory Ayres

Assistant Research Professor

Office
A220 Harper Hall
Notre Dame, IN 46556
Phone
+1 574-631-2601
Email
cayres@nd.edu

Research Areas

  • Biochemistry

Research Specialties

  • Life Processes
  • Theory

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Biography

Year Title
2022-present Assistant Research Professor, University of Notre Dame
2017-2022 Postdoctoral Fellow, University of Notre Dame
2017 Ph.D. in Chemistry & Biochemistry, University of Notre Dame
2011 Sc.B. in Chemistry, Georgia Southern University

Selected Publications

  • Rosenberg, A. M.; Ayres, C. M.; Medina-Cucurella, A. V.; Whitehead, T. A. and Baker, B. M. "Enhanced T Cell Receptor Specificity through Framework Engineering" 2024 Frontiers in Immunology, 15, 1345368. DOI: 10.3389/fimmu.2024.1345368.
  • Custodio, J. M.; Ayres, C. M.; Rosales, T. J.; Brambley, C. A.; Arbuiso, A. G.; Landau, L. M.; Keller, G.; Srivastava, P. K. and Baker, B. M. "Structural and Physical Features that Distinguish Tumor- Controlling from Inactive Cancer Neoepitopes" 2023 Proceedings of the National Academy of Sciences of the United States of America, 120 (51), e2312057120. DOI: 10.1073/pnas.2312057120.
  • Ayres, C. M.; Corcelli, S. A. and Baker, B. M. "The Energetic Landscape of Catch Bonds in TCR Interfaces" 2023 Journal of Immunology, 211 (3), pp.325-332. DOI: 10.4049/jimmunol.2300121.
  • Ayres, C. M. and Baker, B. M. "Peptide-Dependent Tuning of Major Histocompatibility Complex Motional Properties and the Consequences for Cellular Immunity" 2022 Current Opinion in Immunology, 76, 102184. DOI: 10.1016/j.coi.2022.102184.
  • Smith, A. R.; Alonso, J. A.; Ayres, C. M.; Singh, N. K.; Hellman, L. M. and Baker, B. M. "Structurally Silent Peptide Anchor Modifications Allosterically Modulate T Cell Recognition in a Receptor-Dependent Manner" 2021 Proceedings of the National Academy of Sciences of the United States of America, 118 (4), e2018125118. DOI: 10.1073/pnas.2018125118.
  • Ma, J. Q.; Ayres, C. M.; Hellman, L. M.; Devlin, J. R. and Baker, B. M. "Dynamic Allostery Controls the Peptide Sensitivity of the Ly49C Natural Killer Receptor" 2021 Journal of Biological Chemistry, 296, 100686. DOI: 10.1016/j.jbc.2021.100686.