Aktar Ali
Associate Research Professor; Director, Warren Center Biological Screening Core
- Office
- 305B Mccourtney Hall
Notre Dame, IN 46556 - Phone
- +1 574-631-2363
- aali4@nd.edu
Research Areas
- Biochemistry
Research Specialties
- Life Processes
- Medicine
Prospective Graduate Students
Biography
| Year | Title |
|---|---|
| 2021-present | Associate Research Professor; Director, Biological Screening Core, Warren Family Center for Drug Discovery, University of Notre Dame |
| 2018-2021 | Adjunct Teaching Faculty, Richland College |
| 2017-2021 | Co-Director, Mineral Metabolism Laboratory, University of Texas Southwestern Medical Center |
| 2015-2017 | Assistant Professor & Core Director, Biomedical & Obesity Research Core, University of Nebraska |
| 2008-2015 | Assistant Professor & Core Director, Metabolic Phenotyping Core, University of Texas Southwestern Medical Center |
| 2005-2007 | Instructor, University of Texas Southwestern Medical Center |
| 2003-2005 | Associate Research Scientist, Department of Pathology, NYU School of Medicine |
| 2000-2003 | Assistant Research Scientist, Nelson Institute of Environmental Medicine, NYU School of Medicine |
| 1999 | Postdoctoral Fellow, Niigata University of Pharmacy and Applied Life Science, Japan |
| 1999 | Ph.D. in Pharmaceutical Science, Niigata University of Pharmacy and Applied Life Science, Japan |
| 1994 | M.Sc. in Inorganic Chemistry, University of Chittagong, Bangladesh |
| 1991 | B.Sc. in Chemistry, University of Chittagong, Bangladesh |
Selected Publications
- Usama; Khan, Z.; Ali, A.; Shah, M. S. and Imran, M. "Differential Glycosylation in Mutant Vitamin D-Binding Protein Decimates the Binding Stability of Vitamin D" 2023 Journal of Biomolecular Structure & Dynamics DOI: 10.1080/07391102.2023.2226742.
- Tsunezumi, J.; Sugiura, H.; Oinam, L.; Ali, A.; Thang, B. Q.; Sada, A.; Yamashiro, Y.; Kuro-O, M. and Yanagisawa, H. "Fibulin-7, a Heparin Binding Matricellular Protein, Promotes Renal Tubular Calcification in Mice" 2018 Matrix Biology, 74, pp.5-20. DOI: 10.1016/j.matbio.2018.04.014.
- Deng, Y. F.; Wang, Z. V.; Gordillo, R.; Zhu, Y.; Ali, A.; Zhang, C.; Wang, X. D.; Shao, M. L.; Zhang, Z. Z.; Iyengar, P.; Gupta, R. K.; Horton, J. D.; Hill, J. A. and Scherer, P. E. "Adipocyte Xbp1s Overexpression Drives Uridine Production and Reduces Obesity" 2018 Molecular Metabolism, 11, pp.1-17. DOI: 10.1016/j.molmet.2018.02.013.
- Hasan, M.; Gonugunta, V. K.; Dobbs, N.; Ali, A.; Palchik, G.; Calvaruso, M. A.; DeBerardinis, R. J. and Yan, N. "Chronic Innate Immune Activation of TBK1 Suppresses mTORC1 Activity and Dysregulates Cellular Metabolism" 2017 Proceedings of the National Academy of Sciences of the United States of America, 114 (4), pp.746-751. DOI: 10.1073/pnas.1611113114.
- Wang, Q. A.; Tao, C.; Jiang, L.; Shao, M. L.; Ye, R. S.; Zhu, Y.; Gordillo, R.; Ali, A.; Lian, Y.; Holland, W. L.; Gupta, R. K. and Scherer, P. E. "Distinct Regulatory Mechanisms Governing Embryonic Versus Adult Adipocyte Maturation" 2015 Nature Cell Biology, 17 (9), pp.1099. DOI: 10.1038/ncb3217.
- Moore, Z.; Chakrabarti, G.; Luo, X.; Ali, A.; Hu, Z.; Fattah, F. J.; Vemireddy, R.; DeBerardinis, R. J.; Brekken, R. A. and Boothman, D. A. "NAMPT Inhibition Sensitizes Pancreatic Adenocarcinoma Cells to Tumor-Selective, PAR-Independent Metabolic Catastrophe and Cell Death Induced by Beta-Lapachone" 2015 Cell Death & Disease, 6, e1599. DOI: 10.1038/cddis.2014.564.