Cory Ayres

Assistant Research Professor

A220 Harper Hall
Notre Dame, IN 46556
+1 574-631-2601

Research Areas

  • Biochemistry

Research Specialties

  • Life Processes
  • Theory

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Year Title
2022-present Assistant Research Professor, University of Notre Dame
2017-2022 Postdoctoral Fellow, University of Notre Dame
2017 Ph.D. in Chemistry & Biochemistry, University of Notre Dame
2011 Sc.B. in Chemistry, Georgia Southern University

Selected Publications

  • Ayres, C. M. and Baker, B. M. "Peptide-Dependent Tuning of Major Histocompatibility Complex Motional Properties and the Consequences for Cellular Immunity" 2022 Current Opinion in Immunology, 76, 102184. DOI: 10.1016/j.coi.2022.102184.
  • Smith, A. R.; Alonso, J. A.; Ayres, C. M.; Singh, N. K.; Hellman, L. M. and Baker, B. M. "Structurally Silent Peptide Anchor Modifications Allosterically Modulate T Cell Recognition in a Receptor-Dependent Manner" 2021 Proceedings of the National Academy of Sciences of the United States of America, 118 (4), e2018125118. DOI: 10.1073/pnas.2018125118.
  • Ma, J. Q.; Ayres, C. M.; Hellman, L. M.; Devlin, J. R. and Baker, B. M. "Dynamic Allostery Controls the Peptide Sensitivity of the Ly49C Natural Killer Receptor" 2021 Journal of Biological Chemistry, 296, 100686. DOI: 10.1016/j.jbc.2021.100686.
  • Devlin, J. R.; Alonso, J. A.; Ayres, C. M.; Keller, G.; Bobisse, S.; Vander Kooi, C. W.; Coukos, G.; Gfeller, D.; Harari, A. and Baker, B. M. "Structural Dissimilarity from Self Drives Neoepitope Escape from Immune Tolerance" 2020 Nature Chemical Biology, 16 (11), pp.1269. DOI: 10.1038/s41589-020-0610-1.
  • Singh, N. K.; Abualrous, E. T.; Ayres, C. M.; Noe, F.; Gowthaman, R.; Pierce, B. G. and Baker, B. M. "Geometrical Characterization of T Cell Receptor Binding Modes Reveals Class-Specific Binding to Maximize Access to Antigen" 2020 Proteins-Structure Function and Bioinformatics, 88 (3), pp.503-513. DOI: 10.1002/prot.25829.
  • Ayres, C. M.; Abualrous, E. T.; Bailey, A.; Abraham, C.; Hellman, L. M.; Corcelli, S. A.; Noe, F.; Elliott, T. and Baker, B. M. "Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility" 2019 Frontiers in Immunology, 10, 966. DOI: 10.3389/fimmu.2019.00966.