William Boggess

William Boggess

Biography

1994
Ph.D., University of Tennessee
1988
B.S., Davis & Elkins College

Research Interests

Research Support Services

Dr. Boggess maintains the Mass Spectrometry Core Facility of the University. This facility offers a broad range of analyses which include low resolution spectra, high resolution accurate mass measurements, GC/MS, LC/MS, and LC/MS/MS. Ionization techniques available in the core include electron ionization (EI), chemical ionization (CI), fast atom bombardment (FAB) matrix-assisted laser desorption/ionization time-of flight (MALD-TOF), and electrospray ionization (ESI).

Recent Papers

  • Lee, M.; Hesek, D.; Lastochkin, E.; Dik, D. A.; Boggess, B.; Mobashery, S. "Deciphering the Nature of Enzymatic Modifications of Bacterial Cell Walls." Chembiochem 2017, 18, 1696-1702.
  • Lee, M.; Hesek, D.; Dik, D. A.; Fishovitz, J.; Lastochkin, E.; Boggess, B.; Fisher, J. F.; Mobashery, S. "From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa." Angew. Chem. Int. Edit. 2017, 56, 2735-2739.
  • Light, S. H.; Cahoon, L. A.; Mahasenan, K. V.; Lee, M.; Boggess, B.; Halavaty, A. S.; Mobashery, S.; Freitag, N. E.; Anderson, W. F. "Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity." Structure 2017, 25, 295-304.
  • Dik, D. A.; Dominguez-Gil, T.; Lee, M.; Hesek, D.; Byun, B.; Fishovitz, J.; Boggess, B.; Hellman, L. M.; Fisher, J. F.; Hermoso, J. A.; Mobashery, S. "Muropeptide Binding and the X-ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa." J. Am. Chem. Soc. 2017, 139, 1448-1451.
  • Lee, M.; Dhar, S.; De Benedetti, S.; Hesek, D.; Boggess, B.; Blazquez, B.; Mathee, K.; Mobashery, S. "Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of beta-Lactam-Antibiotic Resistance." Angew. Chem. Int. Edit. 2016, 55, 6882-6886.
  • Lee, M.; Chen, Z.; Tomlinson, B. N.; Gooyit, M.; Hesek, D.; Juarez, M. R.; Nizam, R.; Boggess, B.; Lastochkin, E.; Schroeder, V. A.; Wolter, W. R.; Suckow, M. A.; Cui, J.; Mobashery, S.; Gu, Z.; Chang, M. "Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury." ACS Chem. Neurosci. 2015, 6, 1658-1664.

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