Per-Ola Norrby

Per-Ola Norrby

Adjunct Professor

Biography

2014-present
Principal Scientist, AstraZeneca
2006-2014
Professor, University of Gothenburg
2000-2006
Associate Professor, Technical University of Denmark
1997-2000
Associate Professor, Royal Danish School of Pharmacy, Copenhagen, Denmark
1994-1996
Research Associate, Royal Danish School of Pharmacy, Copenhagen, Denmark
1992-1993
Postdoctoral Researcher, Scripps Research Institute

Selected Awards

2004
Eli Lilly Lecturer, University of Notre Dame
2000
Syntheses, Inc. Lecturer, University of Notre Dame
1992
Bengt Lundqvist Memory Award
1985-1989
Ernst Jonsson Graduate Fellowship

Research Interests

My main research interest is broad understanding of chemical reactivity from both an experimental and theoretical viewpoint. With collaborators at Notre Dame, primarily Paul Helquist and Olaf Wiest, I work on understanding and predicting selectivity in catalytic reactions. In my work at AstraZeneca, I focus on understanding and predicting ex-vivo degradation of drugs.

Recent Papers

  • Santilli, C.; Beigbaghlou, S. S.; Ahlburg, A.; Antonacci, G.; Fristrup, P.; Norrby, P.; Madsen, R. "The Manganese-Catalyzed Cross-Coupling Reaction and the Influence of Trace Metals." Eur. J. Org. Chem. 2017, 5269-5274.
  • Stridfeldt, E.; Lindstedt, E.; Reitti, M.; Blid, J.; Norrby, P.; Olofsson, B. "Competing Pathways in O-Arylations with Diaryliodonium Salts: Mechanistic Insights." Chem. Eur. J. 2017, 23, 13249-13258.
  • Antonacci, G.; Ahlburg, A.; Fristrup, P.; Norrby, P.; Madsen, R. "Manganese-Catalyzed Cross-Coupling of Aryl Halides and Grignard Reagents by a Radical Mechanism." Eur. J. Org. Chem. 2017, 4758-4764.
  • Margalef, J.; Coll, M.; Norrby, P.; Pamies, O.; Dieguez, M. "Asymmetric Catalyzed Allylic Substitution Using a Pd/P-S Catalyst Library with Exceptional High Substrate and Nucleophile Versatility: DFT and Pd-pi-allyl Key Intermediates Studies." Organometallics 2016, 35, 3323-3335.
  • Engel, J.; Mersmann, S.; Norrby, P.; Bolm, C. "Mechanistic Insights into the Iridium-Catalyzed Hydrogenations of alpha,beta-Unsaturated Ketones." ChemCatChem 2016, 8, 3099-3106.
  • Stalsmeden, A. S.; Vazquez, J. L. B.; van Weerdenburg, K.; Rae, R.; Norrby, P.; Kann, N. "Glycerol Upgrading via Hydrogen Borrowing: Direct Ruthenium-Catalyzed Amination of the Glycerol Derivative Solketal." ACS Sus. Chem. Eng. 2016, 4, 5730-5736.

Contact Information

Primary Research Areas

Research Specialties