Per-Ola Norrby

Per-Ola Norrby

Adjunct Professor

Biography

2014-present
Principal Scientist, AstraZeneca
2006-2014
Professor, University of Gothenburg
2000-2006
Associate Professor, Technical University of Denmark
1997-2000
Associate Professor, Royal Danish School of Pharmacy, Copenhagen, Denmark
1994-1996
Research Associate, Royal Danish School of Pharmacy, Copenhagen, Denmark
1992-1993
Postdoctoral Researcher, Scripps Research Institute

Selected Awards

2004
Eli Lilly Lecturer, University of Notre Dame
2000
Syntheses, Inc. Lecturer, University of Notre Dame
1992
Bengt Lundqvist Memory Award
1985-1989
Ernst Jonsson Graduate Fellowship

Research Interests

My main research interest is broad understanding of chemical reactivity from both an experimental and theoretical viewpoint. With collaborators at Notre Dame, primarily Paul Helquist and Olaf Wiest, I work on understanding and predicting selectivity in catalytic reactions. In my work at AstraZeneca, I focus on understanding and predicting ex-vivo degradation of drugs.

Recent Papers

  • Lee, J.M.; Zhang, X.; Norrby, P.O.; Helquist, P.; Wiest, O. "Stereoselectivity in (Acyloxy)borane-Catalyzed Mukaiyama Aldol Reactions." J. Org. Chem. 2016, 81(13), 5314-5321.
  • Hansen, E.; Lime, E.; Norrby, P.O.; Wiest, O. "Anomeric Effects in Sulfamides." J. Phys. Chem. A 2016, 120(20), 3677-3682.
  • Hansen, E.; Rosales, A.R.; Tutkowski, B.; Norrby, P.O.; Wiest, O. "Prediction of Stereochemistry using Q2MM." Accounts Chem. Res. 2016, 49(5), 996-1005.
  • Bellini, R.; Magre, M.; Biosca, M.; Norrby, P.O.; Pamies, O.; Dieguez, M.; Moberg, C. "Conformational Preferences of a Tropos Biphenyl Phosphinooxazoline-a Ligand with Wide Substrate Scope." ACS Catalysis 2016, 6(3), 1701-1712.
  • Savela, R.; Grenman, H.; Sundelin, H.; Norrby, P.O.; Murzin, D.Y.; Leino, R. "Kinetic and Theoretical Investigation of Iron(III)-Catalyzed Silane Chlorination." ChemCatChem 2016, 8(3), 584-592.
  • Magre, M.; Biosca, M.; Norrby, P.O.; Pamies, O.; Dieguez, M. "Theoretical and Experimental Optimization of a New Amino Phosphite Ligand Library for Asymmetric Palladium-Catalyzed Allylic Substitution." ChemCatChem 2015, 7(24), 4091-4107.

Contact Information

Primary Research Areas

Research Specialties