Per-Ola Norrby

Per-Ola Norrby

Adjunct Professor


Principal Scientist, AstraZeneca
Professor, University of Gothenburg
Associate Professor, Technical University of Denmark
Associate Professor, Royal Danish School of Pharmacy, Copenhagen, Denmark
Research Associate, Royal Danish School of Pharmacy, Copenhagen, Denmark
Postdoctoral Researcher, Scripps Research Institute

Selected Awards

Eli Lilly Lecturer, University of Notre Dame
Syntheses, Inc. Lecturer, University of Notre Dame
Bengt Lundqvist Memory Award
Ernst Jonsson Graduate Fellowship

Research Interests

My main research interest is broad understanding of chemical reactivity from both an experimental and theoretical viewpoint. With collaborators at Notre Dame, primarily Paul Helquist and Olaf Wiest, I work on understanding and predicting selectivity in catalytic reactions. In my work at AstraZeneca, I focus on understanding and predicting ex-vivo degradation of drugs.

Recent Papers

  • Lee, J.M.; Zhang, X.; Norrby, P.O.; Helquist, P.; Wiest, O. "Stereoselectivity in (Acyloxy)borane-Catalyzed Mukaiyama Aldol Reactions." J. Org. Chem. 2016, 81(13), 5314-5321.
  • Hansen, E.; Lime, E.; Norrby, P.O.; Wiest, O. "Anomeric Effects in Sulfamides." J. Phys. Chem. A 2016, 120(20), 3677-3682.
  • Hansen, E.; Rosales, A.R.; Tutkowski, B.; Norrby, P.O.; Wiest, O. "Prediction of Stereochemistry using Q2MM." Accounts Chem. Res. 2016, 49(5), 996-1005.
  • Bellini, R.; Magre, M.; Biosca, M.; Norrby, P.O.; Pamies, O.; Dieguez, M.; Moberg, C. "Conformational Preferences of a Tropos Biphenyl Phosphinooxazoline-a Ligand with Wide Substrate Scope." ACS Catalysis 2016, 6(3), 1701-1712.
  • Savela, R.; Grenman, H.; Sundelin, H.; Norrby, P.O.; Murzin, D.Y.; Leino, R. "Kinetic and Theoretical Investigation of Iron(III)-Catalyzed Silane Chlorination." ChemCatChem 2016, 8(3), 584-592.
  • Magre, M.; Biosca, M.; Norrby, P.O.; Pamies, O.; Dieguez, M. "Theoretical and Experimental Optimization of a New Amino Phosphite Ligand Library for Asymmetric Palladium-Catalyzed Allylic Substitution." ChemCatChem 2015, 7(24), 4091-4107.

Contact Information

Primary Research Areas

Research Specialties