Merlin Bruening

Merlin Bruening

Concurrent Professor


Concurrent Professor, Department of Chemistry & Biochemistry, University of Notre Dame
Professor, Department of Chemical & Biomolecular Engineering, University of Notre Dame
Professor, Michigan State University
Associate Professor, Michigan State University
Assistant Professor, Michigan State University
NIH Postdoctoral Fellow, Texas A&M University
Ph.D. in Chemistry, The Weizmann Institute of Science
M.S. in Chemistry, Brigham Young University
B.S. in Chemical Engineering, Brigham Young University

Selected Awards

Benedetti-Pichler Award of the American Microchemical Society
MSU Innovation of the Year
MSU College of Natural Science Distinguished Faculty Award
Society for Electroanalytical Chemistry Young Investigator Award

Research Interests

The Bruening Group develops new thin films for specific protein capture in porous membranes, ion separations in electrodialysis, and controlled protein digestion prior to analysis with mass spectrometry. Potential applications include protein purification, antibody characterization and sequencing, and salt purification or recycling.

Recent Papers

  • Zhu, Y.; Ahmad, M.; Yang, L.; Misovich, M.; Yaroshchuk, A.; Bruening, M. L. "Adsorption of polyelectrolyte multilayers imparts high monovalent/divalent cation selectivity to aliphatic polyamide cation-exchange membranes." J. Membr. Sci. 2017, 537, 177-185.
  • Dong, J.; Ning, W.; Liu, W.; Bruening, M. L. "Limited proteolysis in porous membrane reactors containing immobilized trypsin." Analyst 2017, 142, 2578-2586.
  • Yaroshchuk, A.; Bruening, M. L. "An analytical solution of the solution-diffusion-electromigration equations reproduces trends in ion rejections during nanofiltration of mixed electrolytes." J. Membr. Sci. 2017, 523, 361-372.
  • White, N.; Misovich, M.; Alemayehu, E.; Yaroshchuk, A.; Bruening, M. L. "Highly selective separations of multivalent and monovalent cations in electrodialysis through Nafion membranes coated with polyelectrolyte multilayers." Polymer 2016, 103, 478-485.
  • Shi, H.; Xagoraraki, I.; Parent, K. N.; Bruening, M. L.; Tarabara, V. V. "Elution Is a Critical Step for Recovering Human Adenovirus 40 from Tap Water and Surface Water by Cross-Flow Ultrafiltration." Appl. Environ. Microbiol. 2016, 82, 4982-4993.
  • Wijeratne, S.; Liu, W.; Dong, J.; Ning, W.; Ratnayake, N. D.; Walker, K. D.; Bruening, M. L. "Layer-by-Layer Deposition with Polymers Containing Nitrilotriacetate, A Convenient Route to Fabricate Metal- and Protein-Binding Films." ACS Appl. Mater.¬†Inter.¬†2016, 8, 10164-10173.

Contact Information

Primary Research Areas

Research Specialties