Biography

Education:
B.S. 1972, SUNY Stony Brook
Ph. D. 1976, Massachusetts Institute of Technology
 
Experience:
Postdoctoral Fellow 1976-1979, Harvard University
Faculty 1980–1985, University of Minnesota
Scientist 1985–2003, The Upjohn Company
Faculty 2004–current, University of Notre Dame
 

Recent Papers

  • Clay, J.M.; Hesek, D.; Oliver, A.G.; Lee, M.; Fisher, J.F. "Ensemble of Pinanones from the Permanganate Oxidation of Myrtenal" J. Org. Chem. 2016, 81(13), 5705-5709.
  • Leemans, E.; Mahasenan, K.V.; Kumarasiri, M.; Spink, E.; Ding, D.R.; O'Daniel, P.I.; Boudreau, M.A.; Lastochkin, E.; Testero, S.A.; Yamaguchi, T.; Lee, M.; Hesek, D.; Fisher, J.F.; Chang, M.; Mobashery, S. "Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials" Bioorg. Med. Chem. Lett. 2016, 26(3), 1011-1015.
  • Fisher, J.F.; Mobashery, S. "Endless resistance. Endless antibiotics?" MedChemComm 2016, 7(1), 37-49.
  • Lee, M.; Ruci, T.; Hesek, D.; Oliver, A.G.; Fisher, J.F.; Mobashery, S. "Regioselective Control of the SNAr Amination of 5-Substituted-2,4-Dichloropyrimidines Using Tertiary Amine Nucleophiles" J. Org. Chem. 2015, 80(15), 7757-7763.
  • Fishovitz, J.; Taghizadeh, N.; Fisher, J.F.; Chang, M.; Mobashery, S. "The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA)" J. Am. Chem. Soc. 2015, 137(20), 6500-6505.
  • Lee, M.; Hesek, D.; Blazquez, B.; Lastochkin, E.; Boggess, B.; Fisher, J.F.; Mobashery, S. "Catalytic Spectrum of the Penicillin-Binding Protein 4 of Pseudomonas aeruginosa, a Nexus for the Induction of beta-Lactam Antibiotic Resistance" J. Am. Chem. Soc. 2015, 137(1), 190-200.
 

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