Başar Bilgiçer

Başar Bilgiçer

Biophysical Chemistry and Biomolecular Drug Design

Biography

2015-present
Associate Professor, Department of Chemical & Biomolecular Engineering, University of Notre Dame
2015-present
Concurrent Associate Professor, Department of Chemistry & Biochemistry, University of Notre Dame
2008-2015
Assistant Professor, Department of Chemical & Biomolecular Engineering, University of Notre Dame
2008-2015
Concurrent Assistant Professor, Department of Chemistry & Biochemistry, University of Notre Dame
2005-2008
Postdoctoral Fellow, Harvard University
2005
Ph.D. in Chemistry, Tufts University
1998
B.S. in Chemistry, Bogazici University, Turkey

Research Interests

Multivalent biomolecular interactions are very important in biological systems. A deeper understanding of the thermodynamics and kinetics of multivalent interactions in biological systems is imperative in the development of new diagnostic and therapeutic agents. My lab focuses on both understanding the basic dynamic principles of multivalent biomolecular interactions, as well as design of multivalent therapeutic and diagnostic molecules which will deliver novel solutions to complex diseases (e.g. cancer, autoimmune diseases, and allergies).

Recent Papers

  • Mustafaoglu, N.; Kiziltepe, T.; Bilgicer, B. "Site-specific conjugation of an antibody on a gold nanoparticle surface for one-step diagnosis of prostate specific antigen with dynamic light scattering." Nanoscale 2017, 9, 8684-8694.
  • Deak, P. E.; Vrabel, M. R.; Kiziltepe, T.; Bilgicer, B. "Determination of Crucial Immunogenic Epitopes in Major Peanut Allergy Protein, Ara h2, via Novel Nanoallergen Platform." Sci. Rep. 2017, 7, 3981.
  • Ashley, J. D.; Quinlan, C. J.; Schroeder, V. A.; Suckow, M. A.; Pizzuti, V. J.; Kiziltepe, T.; Bilgicer, B. "Dual Carfilzomib and Doxorubicin-Loaded Liposomal Nanoparticles for Synergistic Efficacy in Multiple Myeloma." Mol. Cancer Ther. 2016, 15, 1452-1459.
  • Deak, P. E.; Vrabel, M. R.; Pizzuti, V. J.; Kiziltepe, T.; Bilgicer, B. "Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation." Exp. Biol. Med. 2016, 241, 996-1006.
  • Mustafaoglu, N.; Kiziltepe, T.; Bilgicer, B. "Antibody purification via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule." Analyst 2016, 141, 6571-6582.
  • Mustafaoglu, N.; Aves, N. J.; Bilgicer, B. "Oriented Immobilization of Fab Fragments by Site-Specific Biotinylation at the Conserved Nucleotide Binding Site for Enhanced Antigen Detection." Langmuir 2015, 31, 9728-9736.

Contact Information

Primary Research Areas

Research Specialties