Başar Bilgiçer

Başar Bilgiçer

Biophysical Chemistry and Biomolecular Drug Design

Biography

2015-present
Associate Professor, Dept. of Chemical & Biomolecular Engineering, University of Notre Dame
2015-present
Concurrent Associate Professor, Dept. of Chemistry & Biochemistry, University of Notre Dame
2008-2015
Assistant Professor, Dept. of Chemical & Biomolecular Engineering, University of Notre Dame
2008-2015
Concurrent Assistant Professor, Dept. of Chemistry & Biochemistry, University of Notre Dame
2005-2008
Postdoctoral Fellow, Harvard University
2005
Ph.D. in Chemistry, Tufts University
1998
B.S. in Chemistry, Bogazici University, Turkey

Research Interests

Multivalent biomolecular interactions are very important in biological systems. A deeper understanding of the thermodynamics and kinetics of multivalent interactions in biological systems is imperative in the development of new diagnostic and therapeutic agents. My lab focuses on both understanding the basic dynamic principles of multivalent biomolecular interactions, as well as design of multivalent therapeutic and diagnostic molecules which will deliver novel solutions to complex diseases (e.g. cancer, autoimmune diseases, and allergies).

Recent Papers

  • Deak, P.E., Vrabel, M.R., Kiziltepe, T., Bilgicer, B. "Determination of Crucial Immunogenic Epitopes in Major Peanut Allergy Protein, Ara h2, via Novel Nanoallergen Platform" 2017 Scientific Reports, 7 (1), 3981. DOI: 10.1038/s41598-017-04268-6
  • Mustafaoglu, N., Kiziltepe, T., Bilgicer, B. "Site-specific conjugation of an antibody on a gold nanoparticle surface for one-step diagnosis of prostate specific antigen with dynamic light scattering" 2017 Nanoscale, 9 (25), pp. 8684-8694. DOI: 10.1039/c7nr03096g​​​​​​​
  • Mustafaoglu, N., Kiziltepe, T., Bilgicer, B. "Antibody purification: Via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule" 2016 Analyst, 141 (24), pp. 6571-6582. DOI: 10.1039/c6an02145j
  • Ashley, J.D., Quinlan, C.J., Schroeder, V.A., Suckow, M.A., Pizzuti, V.J., Kiziltepe, T., Bilgicer, B. "Dual Carfilzomib and Doxorubicin-Loaded Liposomal Nanoparticles for Synergistic Efficacy in Multiple Myeloma" 2016 Molecular Cancer Therapeutics, 15 (7), pp. 1452-1459. DOI: 10.1158/1535-7163.MCT-15-0867​​​​​​​
  • Deak, P.E., Vrabel, M.R., Pizzuti, V.J., Kiziltepe, T., Bilgicer, B.​​​​​​​ "Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation" 2016 Experimental Biology and Medicine, 241 (9), pp. 996-1006. DOI: 10.1177/1535370216644533​​​​​​​
  • Mustafaoglu, N., Alves, N.J., Bilgicer, B. "Oriented Immobilization of Fab Fragments by Site-Specific Biotinylation at the Conserved Nucleotide Binding Site for Enhanced Antigen Detection" 2015 Langmuir, 31 (35), pp. 9728-9736. DOI: 10.1021/acs.langmuir.5b01734

Contact Information

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Research Specialties