News

Notre Dame researchers uncover keys to antibiotic resistance in MRSA

Author: Marissa Gebhard

Methicillin-resistant Staphylococcus aureus (MRSA) is shown in the background (in gray). This figure depicts domains and key ligands of the penicillin binding protein 2a — a key resistance enzyme. The red molecule on the right is ceftaroline, a drug recently approved by the FDA.

University of Notre Dame researchers Shahriar Mobashery, Mayland Chang, their team members, and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics.

The work, published in the Proceedings of the National Academy of Sciences, reveals the mechanistic basis for how the MRSA bacterium became such a difficult pathogen over the previous 50 years, in which time it spread rapidly across the world.

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Notre Dame and Moi University join research efforts to shed light on breast cancer

Author: William G. Gilroy

 

 

Strack, student, Harper cancer

Breast cancer is a major health problem worldwide, and the incidence of the disease is rising across Africa. A new joint research effort between Notre Dame’s Eck Institute for Global Health and Harper Cancer Research Institute and a Kenyan doctoral student from Moi University is examining the unique manifestation of breast cancer in Kenya.

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Patricia Clark receives $3.8M NIH collaborative award

Author: Marissa Gebhard

Patricia Clark

Patricia L. Clark, the Rev. John Cardinal O'Hara, C.S.C. Professor of Chemistry and Biochemistry, has received a $3.8M award from the National Institutes of Health (NIH) to lead a pioneering model of collaboration that draws together seven institutions, eight co-PIs and six postdoctoral associates to study macromolecular interactions in living cells. Norm Dovichi, the Grace-Rupley Professor of Chemistry, is also a PI, focusing on separations and single molecule detection. Matthew Champion, a Research Assistant Professor in the Mass Spectrometry and Proteomics Facility, will serve as deputy director of the team.…

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Renee Bouley selected to receive prestigious ACS Predoctoral Fellowship

Author:

Renee Bouley, a third year graduate student in the Department of Chemistry and Biochemistry, has been selected to receive a prestigious American Chemical Society (ACS) Division of Medicinal Chemistry Predoctoral Fellowship. Bouley is one of only four recipients chosen for the 2013-2014 cycle.

This award supports doctoral candidates working in the area of medicinal chemistry who have demonstrated superior achievements as graduate students and who show potential for future work as independent investigators. These fellowships have been awarded annually since 1991 and include one year stipend support and an invitation to present the fellow's research results at a special awards session at the ACS National Meeting.…

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NPC Conference Fosters Research Collaborations, Family Connections

Author:

Olaf Wiest

Some 75 researchers and family members from around the world attended the Michael, Marcia, and Christa Parseghian Scientific Conference for Niemann-Pick Type C on June 13-15 in Jordan Hall on the Notre Dame campus. The event included more than 20 scientific presentations, posters, events for families, and shared receptions.…

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Dovichi earns ANACHEM award from Association of Analytical Chemistry

Author:

Norm Dovichi

Norman Dovichi, the Grace-Rupley Chair of Chemistry and Biochemistry, has received the 2013 ANACHEM Award from the Association of Analytical Chemistry (ANACHEM) for his achievements as an analytical chemist and educator.

The ANACHEM award honors an outstanding analytical chemist who has made significant contributions to the advancement of analytical chemistry. Dovichi, the only chemist named an Unsung Hero of the human genome project by Science in 2001, developed a high-throughput DNA sequencer used for mapping the human genome. His current research focuses on measuring changes in protein content during embryo development, using mass spectrometry technology–how the parts identified in the human genome are assembled.…

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Stahelin Named Showalter Scholar

Author: Zach Richard

Rob Stahelin

Robert V. Stahelin, associate professor of biochemistry and molecular biology at Indiana University School of Medicine-South Bend (IUSM-SB), and Adjunct Associate Professor of Chemistry and Biochemistry at Notre Dame, has been selected as one of four inaugural Showalter Scholars at IUSM.…

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Three Chemistry Faculty Receive Undergraduate Teaching Awards

Author:

Patricia L. Clark, J. Daniel Gezelter and James F. Johnson, from the Department of Chemistry and Biochemistry, are among the 18 winners of Rev. Edmund P. Joyce, C.S.C. Awards for Excellence in Undergraduate Teaching.

The winners of Joyce teaching excellence awards represent faculty who have had a profound influence on undergraduate students through sustained exemplary teaching.…

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Brian Baker named associate editor for Journal of Immunology

Author:

Brian Baker

Brian Baker, associate professor of chemistry and biochemistry and director of graduate studies for the department, has been selected as an associate editor for Journal of Immunology. The journal publishes peer-reviewed articles in all areas of experimental immunology, which includes both basic and clinical studies. All editors of the bi-monthly journal are practicing scientists and the publication is cited more often than any other immunology journal.…

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Young Researchers Present Their Work at Regional Science Fair

From diaper absorbency to the detection of dark matter, student projects addressed a number of life's mysteries recently at the Northern Indiana Regional Science and Engineering Fair (NIRSEF), held in the Stepan Center at the University of Notre Dame.

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Ansel Nalin earns 2013 Weich Award

Chemistry major Ansel Nalin has received the 2013 Norbert L. Wiech Award. The award is presented annually to an outstanding junior who has excelled in academics and undergraduate research at the University of Notre Dame.

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Zachary Schultz named a 2013 Cottrell Scholar

Zachary Schultz, assistant professor of chemistry and biochemistry, has been named a 2013 Cottrell Scholar. Cottrell Scholar Awards are given to early-career professors who have developed excellent research programs and excellent approaches to undergraduate teaching.

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Students solve case in 'CSI'-style project

Students in Marya Lieberman's "Forensic Chemistry" course apply techniques they learned in class in a real-world setting through a 'CSI'-style project with the help of fellow chemistry professor Seth Brown acting as a gunshot victim in the Hesburgh Library.

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