News

In memoriam: Jeremiah P. Freeman, professor emeritus of chemistry and biochemistry

Author: Michael O. Garvey

memoriam_200x200

Jeremiah P. Freeman, professor emeritus of chemistry and biochemistry at the University of Notre Dame, died Feb. 14 (Friday) after a brief illness. He was 84.

A native of Detroit and a graduate of Detroit Catholic Central High School, Freeman began a lifelong career in chemistry while working in his father’s drugstore and discovering that he could obtain a wide variety of chemicals from the store’s suppliers.

Read More

ESTEEM project spotlight: Dr. W. Matthew Leevy

Author: Emily Sussman

Leevy

College of Science’s Professor Matt Leevy’s research is moving to commercialization stage in the market.


Medical Data Printers has recently validated a protocol for the rapid and inexpensive production of high-resolution physical plastic models derived from 3D printing of pre-clinical X-ray Computed Tomography (CT) data sets (in press at J. Vis. Exp). Recent experiments indicate that the company can translate its protocol for use with clinical CT data derived from human patients. Ear/Nose/Throat (ENT) doctors could be provided with personalized, high-resolution, 3D physical models of a given patient’s head in which the airways are preserved, and on which the structure of the sinuses are completely preserved. These models will be used to practice complicated sinus surgeries ahead of an operation, with the goal of reducing overall surgical time on the patient, and reducing errors.…

Read More

A new way to counter ovarian cancer’s drug resistance

Author: Michael Rodio

 

Standing at a microscope in her Harper Hall laboratory, Karen Cowden Dahl, adjunct assistant professor of chemistry and biochemistry at the University of Notre Dame and assistant professor of biochemistry and molecular biology at the Indiana University School of Medicine-South Bend, is scanning through a petri dish filled with cancer cells that could represent a major step forward in ovarian cancer research.

Read More

Prashant Kamat reaches an h-index over 100

Author: Stephanie Healey

Prashant Kamat

Prashant Kamat, the Rev. John A. Zahm, C.S.C. Professor of Science has earned a Hersch-index (h-index) over 100, an achievement attained only by the best and most accomplished scientists.




Read More

Corcelli Accepts Appointment on ACS Graduate Education Advisory Board

Author: Rebecca Hicks

Steve Corcelli

Steven Corcelli, associate professor of chemistry and biochemistry at the University of Notre Dame, has accepted an invitation to serve as Vice-Chair of the Graduate Education Advisory Board (GEAB) of the American Chemical Society (ACS). Corcelli has been a member of the GEAB since 2012.…

Read More

Notre Dame and Loyola join forces against cancer

Author: William G. Gilroy

Karen Dahl lab, Harper Hall

The University of Notre Dame and Loyola University Chicago are joining forces in a multidisciplinary cancer research collaboration.

The goal of the alliance is to provide direct support for revolutionary new cancer research, with the ultimate objective of making cancer a more manageable, and potentially curable, disease.

Read More

Navari accepts World Health Organization assignment

Author: Gail Hinchion Mancini

Rudolph M

Rudolph M. Navari, M.D., Ph.D., FACP, adjunct professor of chemistry and biochemistry at the University of Notre Dame and associate dean and director of the Indiana University School of Medicine-South Bend (IUSM-SB), has accepted a position with the World Health Organization (WHO) to serve as the director of the Cancer Care Program in Eastern Europe. His new role will begin in April 2014.

Read More

Smith named associate editor of Bioconjugate Chemistry

Author: Stephanie Healey

Brad Smith

Brad Smith, the Emil T. Hofman Professor of Science in the Department of Chemistry and Biochemistry, has been named associate editor of Bioconjugate Chemistry, a journal published by the American Chemical Society. The journal focuses on research relevant to all aspects of conjugation chemistry and biochemistry, including the preparation, characterization, and properties of molecular conjugates. His term as associate editor will begin January 1, 2014.



Read More

New Notre Dame research offers new insights into the nature of important human pathogen

Author: William G. Gilroy

Shahriar Mobashery

New research from a team led by Shahriar Mobashery, Navari Family Chair in Life Sciences at the University of Notre Dame, offers an insight into cell wall recycling and virulence of Pseudomonas aeruginosa, an important human pathogen. The research provides a road map for how the post-genomic analyses of biochemical processes will take place to elucidate important metabolic processes.

Read More

Notre Dame research finding may help accelerate diabetic wound healing

Author: William G. Gilroy

Mobashery Lab

University of Notre Dame researchers have, for the first time, identified the enzymes that are detrimental to diabetic wound healing and those that are beneficial to repair the wound.

There are currently no therapeutics for diabetic wound healing. The current standard of care is palliative to keep the wound clean and free of infection. In the United States, 66,000 diabetic individuals each year undergo lower-limb amputations due to wounds that failed to heal.

Read More

Prashant Kamat presents work on low-cost solar cell alternatives

Author: Gene Stowe

Prashant Kamat

Recently Prashant V. Kamat, the Rev. John A Zahm C.S.C. Professor of Science, gave a presentation on low-cost solar-cell alternatives at the annual American Chemical Society meeting in Indianapolis.

Scientists have been searching for ways to make low-cost solar cells—photovoltaic devices that convert light to electricity. Solar-cell technology isn’t new, but the high cost of producing the technology makes it difficult for wide use.…

Read More

Notre Dame researchers uncover keys to antibiotic resistance in MRSA

Author: Marissa Gebhard

Methicillin-resistant Staphylococcus aureus (MRSA) is shown in the background (in gray). This figure depicts domains and key ligands of the penicillin binding protein 2a — a key resistance enzyme. The red molecule on the right is ceftaroline, a drug recently approved by the FDA.

University of Notre Dame researchers Shahriar Mobashery, Mayland Chang, their team members, and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics.

The work, published in the Proceedings of the National Academy of Sciences, reveals the mechanistic basis for how the MRSA bacterium became such a difficult pathogen over the previous 50 years, in which time it spread rapidly across the world.

Read More

Notre Dame and Moi University join research efforts to shed light on breast cancer

Author: William G. Gilroy

 

 

Strack, student, Harper cancer

Breast cancer is a major health problem worldwide, and the incidence of the disease is rising across Africa. A new joint research effort between Notre Dame’s Eck Institute for Global Health and Harper Cancer Research Institute and a Kenyan doctoral student from Moi University is examining the unique manifestation of breast cancer in Kenya.

Read More