News

Corcelli Accepts Appointment on ACS Graduate Education Advisory Board

Author: Rebecca Hicks

Steve Corcelli

Steven Corcelli, associate professor of chemistry and biochemistry at the University of Notre Dame, has accepted an invitation to serve as Vice-Chair of the Graduate Education Advisory Board (GEAB) of the American Chemical Society (ACS). Corcelli has been a member of the GEAB since 2012.…

Read More

Notre Dame and Loyola join forces against cancer

Author: William G. Gilroy

Karen Dahl lab, Harper Hall

The University of Notre Dame and Loyola University Chicago are joining forces in a multidisciplinary cancer research collaboration.

The goal of the alliance is to provide direct support for revolutionary new cancer research, with the ultimate objective of making cancer a more manageable, and potentially curable, disease.

Read More

Navari accepts World Health Organization assignment

Author: Gail Hinchion Mancini

Rudolph M

Rudolph M. Navari, M.D., Ph.D., FACP, adjunct professor of chemistry and biochemistry at the University of Notre Dame and associate dean and director of the Indiana University School of Medicine-South Bend (IUSM-SB), has accepted a position with the World Health Organization (WHO) to serve as the director of the Cancer Care Program in Eastern Europe. His new role will begin in April 2014.

Read More

Smith named associate editor of Bioconjugate Chemistry

Author: Stephanie Healey

Brad Smith

Brad Smith, the Emil T. Hofman Professor of Science in the Department of Chemistry and Biochemistry, has been named associate editor of Bioconjugate Chemistry, a journal published by the American Chemical Society. The journal focuses on research relevant to all aspects of conjugation chemistry and biochemistry, including the preparation, characterization, and properties of molecular conjugates. His term as associate editor will begin January 1, 2014.



Read More

New Notre Dame research offers new insights into the nature of important human pathogen

Author: William G. Gilroy

Shahriar Mobashery

New research from a team led by Shahriar Mobashery, Navari Family Chair in Life Sciences at the University of Notre Dame, offers an insight into cell wall recycling and virulence of Pseudomonas aeruginosa, an important human pathogen. The research provides a road map for how the post-genomic analyses of biochemical processes will take place to elucidate important metabolic processes.

Read More

Notre Dame research finding may help accelerate diabetic wound healing

Author: William G. Gilroy

Mobashery Lab

University of Notre Dame researchers have, for the first time, identified the enzymes that are detrimental to diabetic wound healing and those that are beneficial to repair the wound.

There are currently no therapeutics for diabetic wound healing. The current standard of care is palliative to keep the wound clean and free of infection. In the United States, 66,000 diabetic individuals each year undergo lower-limb amputations due to wounds that failed to heal.

Read More

Prashant Kamat presents work on low-cost solar cell alternatives

Author: Gene Stowe

Prashant Kamat

Recently Prashant V. Kamat, the Rev. John A Zahm C.S.C. Professor of Science, gave a presentation on low-cost solar-cell alternatives at the annual American Chemical Society meeting in Indianapolis.

Scientists have been searching for ways to make low-cost solar cells—photovoltaic devices that convert light to electricity. Solar-cell technology isn’t new, but the high cost of producing the technology makes it difficult for wide use.…

Read More

Notre Dame researchers uncover keys to antibiotic resistance in MRSA

Author: Marissa Gebhard

Methicillin-resistant Staphylococcus aureus (MRSA) is shown in the background (in gray). This figure depicts domains and key ligands of the penicillin binding protein 2a — a key resistance enzyme. The red molecule on the right is ceftaroline, a drug recently approved by the FDA.

University of Notre Dame researchers Shahriar Mobashery, Mayland Chang, their team members, and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics.

The work, published in the Proceedings of the National Academy of Sciences, reveals the mechanistic basis for how the MRSA bacterium became such a difficult pathogen over the previous 50 years, in which time it spread rapidly across the world.

Read More

Notre Dame and Moi University join research efforts to shed light on breast cancer

Author: William G. Gilroy

 

 

Strack, student, Harper cancer

Breast cancer is a major health problem worldwide, and the incidence of the disease is rising across Africa. A new joint research effort between Notre Dame’s Eck Institute for Global Health and Harper Cancer Research Institute and a Kenyan doctoral student from Moi University is examining the unique manifestation of breast cancer in Kenya.

Read More

Patricia Clark receives $3.8M NIH collaborative award

Author: Marissa Gebhard

Patricia Clark

Patricia L. Clark, the Rev. John Cardinal O'Hara, C.S.C. Professor of Chemistry and Biochemistry, has received a $3.8M award from the National Institutes of Health (NIH) to lead a pioneering model of collaboration that draws together seven institutions, eight co-PIs and six postdoctoral associates to study macromolecular interactions in living cells. Norm Dovichi, the Grace-Rupley Professor of Chemistry, is also a PI, focusing on separations and single molecule detection. Matthew Champion, a Research Assistant Professor in the Mass Spectrometry and Proteomics Facility, will serve as deputy director of the team.…

Read More

Renee Bouley selected to receive prestigious ACS Predoctoral Fellowship

Author:

Renee Bouley, a third year graduate student in the Department of Chemistry and Biochemistry, has been selected to receive a prestigious American Chemical Society (ACS) Division of Medicinal Chemistry Predoctoral Fellowship. Bouley is one of only four recipients chosen for the 2013-2014 cycle.

This award supports doctoral candidates working in the area of medicinal chemistry who have demonstrated superior achievements as graduate students and who show potential for future work as independent investigators. These fellowships have been awarded annually since 1991 and include one year stipend support and an invitation to present the fellow's research results at a special awards session at the ACS National Meeting.…

Read More

NPC Conference Fosters Research Collaborations, Family Connections

Author:

Olaf Wiest

Some 75 researchers and family members from around the world attended the Michael, Marcia, and Christa Parseghian Scientific Conference for Niemann-Pick Type C on June 13-15 in Jordan Hall on the Notre Dame campus. The event included more than 20 scientific presentations, posters, events for families, and shared receptions.…

Read More

Dovichi earns ANACHEM award from Association of Analytical Chemistry

Author:

Norm Dovichi

Norman Dovichi, the Grace-Rupley Chair of Chemistry and Biochemistry, has received the 2013 ANACHEM Award from the Association of Analytical Chemistry (ANACHEM) for his achievements as an analytical chemist and educator.

The ANACHEM award honors an outstanding analytical chemist who has made significant contributions to the advancement of analytical chemistry. Dovichi, the only chemist named an Unsung Hero of the human genome project by Science in 2001, developed a high-throughput DNA sequencer used for mapping the human genome. His current research focuses on measuring changes in protein content during embryo development, using mass spectrometry technology–how the parts identified in the human genome are assembled.…

Read More

Stahelin Named Showalter Scholar

Author: Zach Richard

Rob Stahelin

Robert V. Stahelin, associate professor of biochemistry and molecular biology at Indiana University School of Medicine-South Bend (IUSM-SB), and Adjunct Associate Professor of Chemistry and Biochemistry at Notre Dame, has been selected as one of four inaugural Showalter Scholars at IUSM.…

Read More

Three Chemistry Faculty Receive Undergraduate Teaching Awards

Author:

Patricia L. Clark, J. Daniel Gezelter and James F. Johnson, from the Department of Chemistry and Biochemistry, are among the 18 winners of Rev. Edmund P. Joyce, C.S.C. Awards for Excellence in Undergraduate Teaching.

The winners of Joyce teaching excellence awards represent faculty who have had a profound influence on undergraduate students through sustained exemplary teaching.…

Read More